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Typical results (testosterone cycle, 500mg/week for 12 weeks): 10-20 pounds lean muscle gain Significant strength increases (20-30% on major lifts) Rapid visual changes (4-6 weeks) Water retention adds additional weight (5-10 pounds) Why so effective: Direct androgen receptor activation Dramatically increased protein synthesis Enhanced nitrogen retention Suppressed cortisol (catabolic hormone) Increased red blood cell production (better endurance) Compounds ranked by muscle-building power: Trenbolone (most powerful, harshest sides) Testosterone (dose-dependent, versatile) Nandrolone/Deca (solid gains, joint benefits) Dianabol (fast gains, harsh on liver) Anavar (mild gains, relatively safe) The catch: Gains are only partially permanent

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Am J Dermatopathol , 44(4):257259